BARDA is requesting project proposals from product developers for the advanced clinical development and assessment of Next-Generation Therapeutics for COVID-19. BARDA has previously identified a capability gap for therapeutics that provide protection through Pre-exposure Prophylaxis (PrEP) and treatment against new SARS-CoV-2 variants. The purpose of this project is to partner with developers and other organizations to advance the clinical development of Next-Generation Therapeutics for COVID-19.  The goal of this project is to provide better COVID-19 solutions and bolster preparedness and response against future health security threats.

Questions related to this RPP should be directed to the RRPV at rrpv-contracts@ati.org. All technical questions must be submitted by 1pm Eastern on 15 August 2024 to allow for Government response.

Responses to this RPP are due to the RRPV no later than 20 September 2024 by 1pm Eastern, and must be submitted through the BARDA Digital Resources (BDR) RRPV Portal.

All RRPV submissions must be submitted to the BARDA Digital Resources (BDR) RRPV Portal. Offerors may submit, or re-submit, in advance of the deadline. Neither the Government nor the RRPV CMF will make allowances/exceptions for submission problems encountered by the Offeror using system-to-system interfaces. If the Offeror fails to submit the full submission prior to the deadline, the submission may not be accepted. It is the Offeror’s responsibility to ensure a timely and complete submission. Failure to propose your submission on time for any reason may result in the submission not being considered for award.

Access to the BDR RRPV Portal is granted to RRPV Member Organizations by request only.  If your organization are not yet members of the RRPV consortium, please visit the How to Join page to learn more.

The account request process is simple but may take several days for approval and access. To request a BDR RRPV Portal account (first-time user), please contact the RRPV (RRPV@ati.org) and provide a set of basic information (first and last name, email address, and phone number, member organization). Once access to the BDR RRPV Portal account has been confirmed, the Offeror will log in to the Portal (www.rrpv.hhs.gov) using the prescribed two-factor authentication method. Once login is complete, the Offeror will be prompted to verify their user information and basic organization-related data. To request changes to your contact information, please contact RRPV (RRPV@ati.org). The Offeror will then be able to start a new submission and will be prompted to input the submission with other project-specific information. Offerors will be provided an automated confirmation of successful submission of a Proposal.

Documentation and reference materials for the BDR RRPV Portal are available to RRPV Member Organizations from the RRPV Members Only Site (for new users, request access here), and upon request from RRPV@ati.org.

Q&A 2 Release:

Issued: 20 August 2024

Adds: Questions 11-13

Amendment 01 Release:

Issued: 20 August 2024

Due: 20 September 2024 by 1pm Eastern

Changes: Revises Sec. 4.2.1.C.

Q&A 1 Release:

Issued: 20 August 2024

Includes: Questions 1-10

Original RPP Release:

Issued: 05 August 2024

Due: 20 September 2024 by 1pm Eastern